Search Results - oncology

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Optogenetic Control of the Blood Brain Barrier for Drug Delivery (Case 2135)
Principle Investigator:Christopher Moore, PhD, Associate Professor Department of NeuroscienceBrown UniversityBrief Description:The blood-brain-barrier (BBB) blocks approximately 98% of small molecule therapeutics and almost 100% of large molecular therapeutics from reaching the central nervous system, creating a challenge in drug delivery for treatment...
Published: 4/28/2020   |   Inventor(s): Christopher Moore, Tyler Brown
Keywords(s):  
Category(s): Engineering and Sensors, Drug Delivery, Neuroscience, Oncology, Therapeutics
Improved Method of Manufacturing Nanowire Nanoarray Memories (Case 1709)
Principal Investigator: John Savage, PhD, Professor Department of Computer ScienceBrown UniversityProvidence, RIBrief Description:Methods have been developed for growing nanowires (NWs) and carbon nanotubes (NTs) with diameters of a few nanometers and for assembling NWs into nanoarrays, crossbars containing two orthogonal sets of parallel wires on...
Published: 4/28/2020   |   Inventor(s): John Savage, Eric Rachlin, Andre Dehon, Charles Lieber
Keywords(s):  
Category(s): Devices, Diagnostics, Engineering and Sensors, Environmental, Metabolic diseases, Nanotechnology, Neuroscience, Oncology, Research Tools, Software, Stem Cells and Regenerative Medicine
Optimized, Cost Effective X-Ray Imaging that Rivals MRI: X-Ray Spatial Frequency Heterodyne Imaging with Protein-Based “Nanobubble” Contrast Agents
Principal Investigator: Christoph Rose-Petruck, PhD, ProfessorDepartment of ChemistryBrown UniversityProvidence, RIBrief Description:Spatial Frequency Heterodyne Imaging (SFHI) is a novel x-ray scatter imaging technique that utilizes nanoparticle contrast agents. Previous studies on SFHI have utilized only metal nanoparticle contrast agents such as...
Published: 4/8/2020   |   Inventor(s): Christoph Rose-Petruck, Trevor Douglas, Danielle Rand, Masaki Uchida
Keywords(s):  
Category(s): Diagnostics, Drug Delivery, Instruments, Nanotechnology, Oncology, Research Tools
Optimized, Cost Effective X-Ray Imaging that Rivals MRI: X-Ray Scatter Imaging of Nanoparticle-Labeled Tissues for Early Cancer Detection (Case 2093)
Principal Investigators:Christoph Rose-Petruck, PhD, ProfessorDepartment of ChemistryBrown UniversityProvidence, RIJack R. Wands, MD, ProfessorBio Med Molecular, Microbiology & ImmunologyBrown UniversityRhode Island HospitalProvidence, RIZoltan Derdak, MD, Assistant ProfessorBio Med MedicineBrown UniversityRhode Island HospitalProvidence, RIBrief...
Published: 4/7/2020   |   Inventor(s): Christoph Rose-Petruck, Danielle Rand, Zoltan Derdak, Jack Wands
Keywords(s):  
Category(s): Oncology, Diagnostics, Nanotechnology
Intra Cellular Delivery of Small Molecules Using Novel Nanotechnology (Case 2060)
Affiliation: Brown UniversityProvidence, RIBrief Description: Pursuit of improved drug delivery vehicles continues to expand and grow with research focusing on a wide variety of approaches and necessary parameters, e.g., injectables, biocompatibility/degradability/availability, materials - polymers and nanoparticles...
Published: 2/2/2017   |   Inventor(s): Thomas Webster
Keywords(s):  
Category(s): Diagnostics, Drug Delivery, Metabolic diseases, Nanotechnology, Neuroscience, Oncology, Research Tools, Stem Cells and Regenerative Medicine
New and Improved Antibacterial Compounds (Case 2062)
Principal Investigator:Jason Sello, PhD, Assistant ProfessorDepartment of Chemistry Brown UniversityProvidence, RIBrief Description: Infectious diseases are the second leading cause of death – globally. Antibiotic drug resistance is a major clinical and societal problem, with many...
Published: 8/19/2015   |   Inventor(s): Jason Sello
Keywords(s):  
Category(s): Drug Delivery, Metabolic diseases, Oncology
Screening Method for Inhibitors of Multidrug-Resistance Transporters (Case 2079)
Principal Investigator: Jeffrey Morgan, PhD, ProfessorDepartment of Bio Med Molecular Pharmacology, Physiology and BiotechnologyBrown UniversityProvidence, RIBrief Description:Multidrug-resistance transporters (MDR) are protein pumps that are up regulated in diseased cells such as those in cancer patients. These proteins actively pump out beneficial...
Published: 8/16/2012   |   Inventor(s): Jeffrey Morgan, Anubhav Tripathi, Toni-Marie Achilli (formerly Ferrucc, Stephanie Mccalla
Keywords(s):  
Category(s): Drug Delivery, Oncology, Research Tools, Diagnostics, Metabolic diseases
Advanced, Wireless, Implantable Neural Recording and Stimulation Microsystem (Case 2032)
Principal Investigator:Arto Nurmikko, PhD, ProfessorSchool of EngineeringBrown UniversityProvidence, RIBrief Description:With the advent of advanced materials, MEMs, microfluidics, nanotechnology and interdisciplinary research programs between engineering fields and the biomedical sciences, miniaturized, next generation devices are now being developed...
Published: 6/20/2012   |   Inventor(s): Arto Nurmikko
Keywords(s):  
Category(s): Devices, Diagnostics, Drug Delivery, Engineering and Sensors, Metabolic diseases, Nanotechnology, Neuroscience, Oncology, Research Tools, Stem Cells and Regenerative Medicine
Interactive, Multilayer, Multivalued Volume-Rendering for Superior 3D Images from MRI or Other Data (Case 1492)
Principal Investigator:David Laidlaw, PhD, ProfessorDepartment of Computer ScienceBrown UniversityProvidence, RIBrief Description:Magnetic resonance imaging (MRI) is a well-established and powerful technique for elucidating structure and is used, for example, in medical applications to discriminate between normal and pathological tissue. The MRI image...
Published: 6/11/2012   |   Inventor(s): David Laidlaw, Andreas Wenger
Keywords(s):  
Category(s): Devices, Diagnostics, Engineering and Sensors, Instruments, Metabolic diseases, Neuroscience, Oncology, Research Tools, Software, Stem Cells and Regenerative Medicine
Improved, Scalable, Optical Particle/Molecule Detector System by Solid State Energy Sources (Case 1494)
Principal Investigator:Arto Nurmikko, PhD, ProfessorSchool of EngineeringBrown UniversityProvidence, RIBrief Description:With environmental safety and defense/bioterrorism concerns, and the continuing drive for important medical breakthroughs, quick and accurate particle diagnostic capabilities have become increasingly important to identify and quantify...
Published: 6/11/2012   |   Inventor(s): Arto Nurmikko, Richard Chang
Keywords(s):  
Category(s): Devices, Diagnostics, Energy, Engineering and Sensors, Environmental, Instruments, Metabolic diseases, Nanotechnology, Neuroscience, Oncology, Research Tools, Stem Cells and Regenerative Medicine
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