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An Accurate Visualization of Specimens Under Centrifuge Via an Extensible Slit Scan Technique (Case 2160)

Affiliation: Marine Biological Laboratory (MBL) Woods Hole, MA Brief Description: Like most microscopes, current centrifuge microscopes must rely on a light source for visualization. Due to the natural of the centrifuge and its intrinsic rotational jitter, the pulse-emitting light source used is not entirely stable, resulting the blur...

Published: Mar 26, 2013 | Inventor(s): Shinya Inoue, Keisuke Suzuki

Keywords(s):

Category(s): Devices, Engineering and Sensors, Instruments, Research Tools

A novel transmitted-light microscope system with broad applicability (Case 2149) A novel transmitted-light microscope system with broad applicability A novel transmitted-light microscope system with broad applicability

Affiliation: Marine Biological Laboratory (MBL) Woods Hole, MA Brief Description: There has been interest in the use of transmission light microscopy over more traditional reflected light microscopy, especially in regards to in situ measurements. While there are endoscopes and laproscopes currently on the market, these rely on the gen...

Published: Mar 26, 2013 | Inventor(s): Robert Silver

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Category(s): Devices, Engineering and Sensors, Instruments, Research Tools

MicroRNA Markers of Ovarian Cancer Metastasis – Diagnostic and Therapeutic (Case 2006)

Principal Investigator: Alexander Brodsky, PhD, Assistant Professor – Medical Science Department of Bio Med Molecular, Cellular Biology Biochemistry Brown University Providence, RI Brief Description: Epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy, affecting...

Published: Nov 14, 2012 | Inventor(s): Laurent Brard, Alexander Brodsky, Katrin Kristjansdottir, Shannon Maclaughlan, Andrew Fischer

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Category(s): Diagnostics, Oncology, Research Tools, Therapeutics

Generalized Two-Frame 3D PTV (Case 2109)

Principal Investigators: Peter Schultz, PhD, Professor Department of Geological Sciences Brown University Providence, RI Brief Description: Particle tracking velocimetry (PTV) is a field of imaging techniques that allows determination of instantaneous velocity and location of particle...

Published: Nov 13, 2012 | Inventor(s): Peter Schultz, Brendan Hermalyn

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Category(s): Engineering and Sensors, Instruments, Research Tools, Software

Screening Method for Inhibitors of Multidrug-Resistance Transporters (Case 2079)

Principal Investigators: Jeffrey Morgan, PhD, Associate Professor – Medical Science Department of Bio Med Molecular Pharmacology, Physiology and Biotechnology Brown University Providence, RI Brief Description: Multidrug-resistance transporters (MDR) are protein pumps that are up regulated in diseased cells such as those in cancer pat...

Published: Aug 16, 2012 | Inventor(s): Jeffrey Morgan, Anubhav Tripathi, Toni-Marie Achilli (formerly Ferrucc, Stephanie McCalla

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Category(s): Drug Delivery, Instruments, Oncology, Research Tools

A New Method for Blotless TEM Imaging ( Case 2066)

Anubhav Tripathi, PhD, Associate Professor School of Engineering Brown University Providence, RI Brief Description: Transmission electron microscopy (TEM) is a useful imaging technique whereby a beam of electrons creates an image as it transmits through an ultra‐thin specimen. The benefit of this imaging technique is that TEM syst...

Published: Aug 9, 2012 | Inventor(s): Anubhav Tripathi, Jinkee Lee, Arijit Bose

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Category(s): Devices, Engineering and Sensors, Instruments, Nanotechnology, Research Tools, Software

Advanced, Wireless, Implantable Neural Recording and Stimulation Microsystem (Case 2032)

Principal Investigator: Arto Nurmikko, PhD, Professor School of Engineering Brown University Providence, RI Brief Description: With the advent of advanced materials, MEMs, microfluidics, nanotechnology and interdisciplinary research programs between engineering fields and the biomedical sciences, miniaturized, next generation devices...

Published: Jun 20, 2012 | Inventor(s): Arto Nurmikko

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Category(s): Devices, Diagnostics, Drug Delivery, Engineering and Sensors, Metabolic diseases, Nanotechnology, Neuroscience, Oncology, Research Tools, Stem Cells and Regenerative Medicine

Novel Therapeutic Class of Small Molecule Drugs for Neurotoxic Injury (Case 1152)

Principal Investigator: Wayne Bowen, PhD, Chairman and Professor Department of Bio Med Molecular Pharmacology, Physiology and Biotechnology Brown University Providence, RI Brief Description: Brain tissue is particularly sensitive to oxygen or energy deprivation unlike many other tissues that can survive extended periods of hypoxia...

Published: Jun 20, 2012 | Inventor(s): Wayne Bowen

Keywords(s):

Category(s): Neuroscience, Research Tools, Therapeutics

Improved Method of Manufacturing Nanowire Nanoarray Memories (Case 1709)

Principal Investigator: John Savage, PhD, Professor Department of Computer Science Brown University Providence, RI Brief Description: Methods have been developed for growing nanowires (NWs) and carbon nanotubes (NTs) with diameters of a few nanometers and for assembling NWs into nanoarrays, crossbars containing two orthogonal se...

Published: Jun 20, 2012 | Inventor(s): John Savage, Eric Rachlin, Andre Dehon, Charles Lieber

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Category(s): Devices, Diagnostics, Engineering and Sensors, Environmental, Metabolic diseases, Nanotechnology, Neuroscience, Oncology, Research Tools, Software, Stem Cells and Regenerative Medicine

QD Color Tunable Laser (Case 2083)

Principal Investigator: Arto Nurmikko, PhD, Professor School of Engineering Brown University Providence, RI Brief Description: Semiconductor lasers have not yet been able to penetrate the full visible spectrum using a single material system for red, green and blue (RGB) in a seamless and optimized way. There is a need for advanced fu...

Published: Jun 11, 2012 | Inventor(s): Arto Nurmikko, Cuong Dang, Joonhee Lee

Keywords(s):

Category(s): Engineering and Sensors, Nanotechnology, Research Tools, Devices

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