Search Results - david+karambizi

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Inhibition of FTO with Entacapone to Treat Glioblastoma

Overview Glioblastoma is one of the most aggressive and lethal human tumors. We are investigating the use of an FDA-approved drug, Entacapone, to treat glioma tumors. Market Opportunity Glioblastoma, one of the most aggressive forms of cancer, has a survival rate of only 14–15 months after diagnosis. There is an urgent need for effective therapies...

Published: 10/15/2022 | Inventor(s): Nikolaos (Nikos) Tapinos, John Zepecki, David Karambizi

Keywords(s):

Category(s): Oncology, Therapeutics

HDAC-7 as novel therapeutic target for human glioblastoma

Overview Glioblastoma is one of the most aggressive and lethal human tumors. We have identified histone deacetylase 7 (HDAC-7) as a potential therapeutic target, a crucial first step toward development of an effective treatment for glioblastoma. Market Opportunity Glioblastoma is the most malignant and aggressive primary brain tumor, with a survival...

Published: 10/15/2022 | Inventor(s): Nikolaos (Nikos) Tapinos, Ola Hassan, David Karambizi

Keywords(s):

Category(s): Therapy Targets, Oncology