Search Results - neuroscience

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Peel-Away Electrode Placement Catheter for Deep Brain Stimulation (DBS)
­Brown’s Laboratory for Neurophysiology and Neuromodulation The Laboratory for Neurophysiology and Neuromodulation studies neural circuits in humans and nonhuman animal models to understand action planning, learning, and high-level cognition, to place neurological and psychiatric dysfunction into these mechanistic contexts, and to design...
Published: 11/1/2021   |   Inventor(s): Wael Asaad, Shane Lee, Owen Leary, Noah Trac, Zakir Tahiry, Rohan Rastogi
Keywords(s):  
Category(s): Central Nervous System(CNS), Devices, Neuroscience
Continuous motor task for objectively quantifying motor symptoms in movement disorders
­Brown’s Laboratory for Neurophysiology and Neuromodulation The Laboratory for Neurophysiology and Neuromodulation studies neural circuits in humans and nonhuman animal models to understand action planning, learning, and high-level cognition, to place neurological and psychiatric dysfunction into these mechanistic contexts, and to design...
Published: 11/1/2021   |   Inventor(s): Wael Asaad, Shane Lee, Minkyu Ahn, James Yu, Daniel Amaya, David Liu, Peter Lauro
Keywords(s):  
Category(s): Central Nervous System(CNS), Neuroscience, Devices
Novel Compounds for Treatment of Neurodegenerative Conditions and Diseases (Case 1939)
Novel Compounds for Treatment of Neurodegenerative Conditions and Diseases Overview Stroke and other neurological insults entail a build-up of waste materials in brain cells. One of the most common waste materials is glutamate, which is present in more than 50 percent of nervous tissue. Glutamate receptors are critical to neuronal functioning. Failure...
Published: 8/11/2021   |   Inventor(s): John Marshall, Mark Spaller, Dennis Goebel
Keywords(s):  
Category(s): Neuroscience, Research Tools, Therapeutics
Method to Predict and Diagnose Seizures and Other Neurological Events (Case 2045)
Method to Predict and Diagnose Seizures and Other Neurological Events Overview Though epilepsy is a common neurological disorder, the medical community still struggles to define and understand seizures and related neurological events. Our method uses implanted microelectrode arrays to predict and detect neurological events—a crucial first step...
Published: 2/3/2021   |   Inventor(s): John Donoghue, Leigh Hochberg, Wilson Truccolo
Keywords(s):  
Category(s): Diagnostics, Instruments, Neuroscience, Software
Optogenetic Control of the Blood Brain Barrier for Drug Delivery (Case 2135)
Optogenetic Control of the Blood Brain Barrier for Drug Delivery Overview The blood–brain barrier (BBB) remains a significant impediment to drug development for central nervous system (CNS) disorders. Our novel method provides a way to regulate the permeability of the BBB, enabling delivery of therapeutics to the brain with high spatial and temporal...
Published: 4/28/2020   |   Inventor(s): Christopher Moore, Tyler Brown
Keywords(s):  
Category(s): Engineering and Sensors, Drug Delivery, Neuroscience, Oncology, Therapeutics
Intracranial Fixation Device for Probes and Catheters (Case 2253)
Brown’s Laboratory for Neurophysiology and Neuromodulation The Laboratory for Neurophysiology and Neuromodulation studies neural circuits in humans and nonhuman animal models to understand action planning, learning, and high-level cognition, to place neurological and psychiatric dysfunction into these mechanistic contexts, and to design improved...
Published: 4/28/2020   |   Inventor(s): Wael Asaad, David Segar
Keywords(s):  
Category(s): Central Nervous System(CNS), Devices, Neuroscience
Improved Method of Manufacturing Nanowire Nanoarray Memories (Case 1709)
Principal Investigator: John Savage, PhD, Professor Department of Computer ScienceBrown UniversityProvidence, RIBrief Description:Methods have been developed for growing nanowires (NWs) and carbon nanotubes (NTs) with diameters of a few nanometers and for assembling NWs into nanoarrays, crossbars containing two orthogonal sets of parallel wires on...
Published: 4/28/2020   |   Inventor(s): John Savage, Eric Rachlin, Andre Dehon, Charles Lieber
Keywords(s):  
Category(s): Devices, Diagnostics, Engineering and Sensors, Environmental, Metabolic diseases, Nanotechnology, Neuroscience, Oncology, Research Tools, Software, Stem Cells and Regenerative Medicine
Minimally-Invasive and Activity Dependent Control of Excitable Neurons (Case 2333)
Principal Investigator:Christopher Moore, PhD, Associate ProfessorDepartment of NeuroscienceBrown UniversityProvidence, RIBrief Description:Abnormal cellular bursting is involved in a number of disease states. These include Parkinson’s Disease, affecting 1 million Americans and incurring an annual cost of $25 billion, and epilepsy, affecting 2...
Published: 3/30/2020   |   Inventor(s): Christopher Moore, Ute Hochgeschwender
Keywords(s):  
Category(s): Neuroscience, Therapeutics
Intra Cellular Delivery of Small Molecules Using Novel Nanotechnology (Case 2060)
Versatile, Robust Nanotube Delivery of siRNA and Nucleic Acid into Cells Overview The use of small interfering RNA (siRNA), which silences gene expression, holds great clinical promise for the treatment of a variety of diseases. Researchers have been exploring the clinical potential of siRNAs for over two decades, and the first siRNA-based therapeutic,...
Published: 2/2/2017   |   Inventor(s): Thomas Webster
Keywords(s):  
Category(s): Diagnostics, Drug Delivery, Metabolic diseases, Nanotechnology, Neuroscience, Oncology, Research Tools, Stem Cells and Regenerative Medicine
Fully Mobile Virtual Reality System (Case 2242)
Principal Investigators:William Warren, PhD, ProfessorDepartment of Cognitive, Linguistic, and Psychological SciencesGabriel Taubin, PhD, Associate Professor School of of EngineeringBrown UniversityProvidence, RIBrief Description:Virtual Reality is here. High-speed, high-definition, low-cost, thrilling VR has arrived. With Facebook’s purchase...
Published: 11/24/2015   |   Inventor(s): William Warren, Michael William Fitzgerald
Keywords(s):  
Category(s): Devices, Software, Neuroscience
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