Search Results - Drug Delivery

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Variants in the CREBRF gene and obesity (Case 2383)
Principal Investigator:Stephen T. McGarveyProfessor of Epidemiology, School of Public HealthBrown UniversityProvidence, RI Brief Description:The technology is a biomarker for predicting genetic risk for obesity and may be useful as a tool in drug discovery for personalizing pharmacotherapeutic approaches to treating obesity. According to the Instit...
Published: 4/26/2017   |   Inventor(s): Stephen Mcgarvey, Daniel Weeks, Ranjan Deka, Nicola Hawley, Ryan Lee Minster, Zsolt Urban, Chi-Ting Su, Erin Kershaw
Category(s): Drug Delivery
New Composition for Biologics (Case 2289)
Principal Investigator(s):Edith Mathiowitz, Ph.D.Professor of Medical Science and EngineeringDirector of the Graduate Program in BiotechnologyBrown UniversityProvidence, RIBrief Description:The market for protein/peptide-based therapeutics has become decidedly established in the past decade, although the gastrointestinal tract causes a significant ...
Published: 2/10/2017   |   Inventor(s): Edith Mathiowitz, Nejat Egilmez, Stacia Furtado, Thomas Conway
Category(s): Drug Delivery
Tunable Antimicrobial-Loaded Gellan Hydrogels for Burn Wound Dressings/Infections (Case 2327)
Principal Investigator(s):Anita ShuklaAssistant Professor of EngineeringAssistant Professor of Molecular Pharmacology, Physiology and BiotechnologyBrown UniversityProvidence, RIBrief Description:Bacterial infection is a very common complication in all classes of wounds. Although all wounds are at risk of infection, burns seem to carry a particular ...
Published: 2/10/2017   |   Inventor(s): Anita Shukla, Shashank Shukla
Category(s): Drug Delivery
Intra Cellular Delivery of Small Molecules Using Novel Nanotechnology (Case 2060)
Affiliation: Brown UniversityProvidence, RIBrief Description: Pursuit of improved drug delivery vehicles continues to expand and grow with research focusing on a wide variety of approaches and necessary parameters, e.g., injectables, biocompatibility/degradability/availability, materials - polymers and n...
Published: 2/2/2017   |   Inventor(s): Thomas Webster
Category(s): Diagnostics, Drug Delivery, Metabolic diseases, Nanotechnology, Neuroscience, Oncology, Research Tools, Stem Cells and Regenerative Medicine
Optogenetic Control of the Blood Brain Barrier for Drug Delivery (Case 2135)
Principle Investigator:Christopher Moore, PhD, Associate Professor Department of NeuroscienceBrown UniversityBrief Description:The blood-brain-barrier (BBB) blocks approximately 98% of small molecule therapeutics and almost 100% of large molecular therapeutics from reaching the central nervous system, creating a challenge in drug delivery for treat...
Published: 11/24/2015   |   Inventor(s): Christopher Moore, Tyler Brown
Category(s): Engineering and Sensors, Drug Delivery, Neuroscience, Oncology, Therapeutics
New and Improved Antibacterial Compounds (Case 2062)
Principal Investigator:Jason Sello, PhD, Assistant ProfessorDepartment of Chemistry Brown UniversityProvidence, RIBrief Description: Infectious diseases are the second leading cause of death – globally. Antibiotic drug resistance is a major clinical and societal problem, with m...
Published: 8/19/2015   |   Inventor(s): Jason Sello
Category(s): Drug Delivery, Metabolic diseases, Oncology
Optimized, Cost Effective X-Ray Imaging that Rivals MRI: X-Ray Spatial Frequency Heterodyne Imaging with Protein-Based “Nanobubble” Contrast Agents (Case 2292)
Principal Investigator: Christoph Rose-Petruck, PhD, ProfessorDepartment of ChemistryBrown UniversityProvidence, RIBrief Description:Spatial Frequency Heterodyne Imaging (SFHI) is a novel x-ray scatter imaging technique that utilizes nanoparticle contrast agents. Previous studies on SFHI have utilized only metal nanoparticle contrast agents such a...
Published: 2/23/2015   |   Inventor(s): Christoph Rose-Petruck, Trevor Douglas, Danielle Rand, Masaki Uchida
Category(s): Diagnostics, Drug Delivery, Instruments, Nanotechnology, Oncology, Research Tools
Unique 3D Biomimetic Nanosurfaces for Growing Cells and Producing Cellular Implants (Case 1696)
Principal Investigator:Diane Hoffman-Kim, PhD, Associate Professor Department of Bio Med Molecular Pharmacology, Physiology and BiotechnologyBrown UniversityProvidence, RIBrief Description:An extensive list of polymers – natural and synthetic – has been utilized in drug delivery and in biomedical engineering for many years, especiall...
Published: 2/6/2015   |   Inventor(s): Diane Hoffman-Kim
Category(s): Stem Cells and Regenerative Medicine, Devices, Drug Delivery, Nanotechnology, Research Tools, Therapeutics
Innovative Sublithographic Nanoscale Interfaces and Memory Architecture (Case 1545)
Principal Investigators: John Savage, PhD, ProfessorDepartment of Computer ScienceBrown UniversityProvidence, RIBrief Description:As computing devices become ever smaller, so do the accompanying microelectronic circuit boards and components. New advanced techniques beyond the conventional lithography of silicon for etching patterns and circuits i...
Published: 1/9/2015   |   Inventor(s): John Savage
Category(s): Devices, Drug Delivery, Engineering and Sensors, Nanotechnology, Research Tools
Targeted, Ferritin-based Molecular MR Imaging Probe for Cancer Detection and Treatment (EA) (Case 2129)
Principal Investigator: Edward Walsh, PhD, Assistant ProfessorDepartment of Bio Med Neuroscience & Diagnostic ImagingBrown UniversityProvidence, RIBrief Description:Lack of effective diagnosis and treatment of cancers such as colorectal, prostate, breast, lung, and liver cancer presents a great need for relevant technology. The market urgently...
Published: 11/3/2014   |   Inventor(s): Edward Walsh, William Keun Chan Park, David Mills
Category(s): Diagnostics, Oncology, Therapeutics, Drug Delivery, Research Tools
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