Search Results - dahlia+alkekhia

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Novel Chromogenic Beta-Lactamase Substrate for Diagnostic Biomaterials

Overview Chromogenic beta-lactamase substrates are used to diagnose bacterial infections. Yet those currently available lose their diagnostic color-change capability when chemically modified. We have synthesized a novel chromogenic beta-lactam molecule (“ANT”) that retains its color-change response when modified for conjugation to a range...

Published: 11/21/2022 | Inventor(s): Anita Shukla, Dahlia Alkekhia, Shashank Shukla, Hannah Safford

Keywords(s):

Category(s): Diagnostics, Drug Delivery

𝜷‐Lactamase-Responsive Degradable Hydrogels

Overview Antibiotic-resistance poses a serious public health problem. We have developed a hydrogel (hydrated polymer network) that is sensitive to β-lactamases, a class of enzymes released by a variety of harmful bacteria. In the presence of β-lactamases, the hydrogel degrades, releasing the therapeutic agent it contains. Market Opportunity The...

Published: 10/17/2022 | Inventor(s): Anita Shukla, Dahlia Alkekhia, Chao Yu

Keywords(s):

Category(s): Drug Delivery