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Parenteral and oral delivery of antibodies
Overview With their high molecular weight and susceptibility to degradation by both enzymes and extreme pH values, proteins such as antibodies usually display poor absorption across epithelial membranes and low oral bioavailability. We have invented pharmaceutical compositions that contain micronized antibodies encapsulated and/or dispersed in polymeric...
Published: 2/22/2024
|
Inventor(s):
Edith Mathiowitz
,
Aharon Azagury
,
Stacia Furtado
,
Yumiko Mizuno
Keywords(s):
Category(s):
Drug Delivery
New Composition for Biologics (Case 2289)
Principal Investigator(s):Edith Mathiowitz, Ph.D.Professor of Medical Science and EngineeringDirector of the Graduate Program in BiotechnologyBrown UniversityProvidence, RIBrief Description:The market for protein/peptide-based therapeutics has become decidedly established in the past decade, although the gastrointestinal tract causes a significant drug-delivery...
Published: 4/14/2020
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Inventor(s):
Edith Mathiowitz
,
Nejat Egilmez
,
Stacia Furtado
,
Thomas Conway
Keywords(s):
Category(s):
Drug Delivery
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