Search Results - carolina+haass-koffler

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Yohimbine Rescue in Unidentified Drug Overdose

Overview Xylazine is an emerging national threat with no xylazine antidotes in use for human drug overdoses. Drug overdose deaths in the United States have been steadily rising since 2019. Technology Researchers at Brown University have developed the use of alpha 2 adrenergic antagonists such as yohimbine for use in the reversal of drug overdose...

Published: 3/6/2025 | Inventor(s): Carolina Haass-Koffler, Elinore McCance-Katz

Keywords(s):

Category(s): Drug Delivery

Development and Use of a High-Throughput Screen to Identify Novel Modulators of the Corticotropin Releasing Factor Binding Protein

Development of a HT Screen to Identify Novel Modulators of the CRFBP Overview A connection between the corticotropin signaling pathway and alcohol use disorder (AUD) has been shown previously. We developed a high throughput screen to identify small molecule modulators of this pathway as potential therapeutics for AUD. Market Opportunity Currently...

Published: 2/22/2022 | Inventor(s): Carolina Haass-Koffler

Keywords(s):

Category(s): Drug Discovery Platform, Central Nervous System(CNS)