Search Results - aharon+azagury

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Parenteral and oral delivery of antibodies

Overview With their high molecular weight and susceptibility to degradation by both enzymes and extreme pH values, proteins such as antibodies usually display poor absorption across epithelial membranes and low oral bioavailability. We have invented pharmaceutical compositions that contain micronized antibodies encapsulated and/or dispersed in polymeric...

Published: 2/22/2024 | Inventor(s): Edith Mathiowitz, Aharon Azagury, Stacia Furtado, Yumiko Mizuno

Keywords(s):

Category(s): Drug Delivery

Composition for Increased Systemic Uptake of Nanoparticles Following Oral or Mucosal Drug Delivery

Overview The use of oral drug delivery systems based on polymeric particles has been historically limited by stomach acidity, enzymatic activity, and low penetration through the GI tissue. We have invented pharmaceutical formulations containing coated particles that have increased systemic uptake into the blood and/or increased local GI uptake. The...

Published: 6/7/2023 | Inventor(s): Edith Mathiowitz, Aharon Azagury, Kosta Milovanovic, Cameron Baptista, Carder Jones

Keywords(s):

Category(s): Drug Delivery