Search Results - anubhav+tripathi

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Novel Electrical Device to Dissociate Tissue Sections into Single Cells for Downstream Single-Cell Analysis

Overview Single-cell analysis is an important analytical tool for studying heterogeneous cellular populations, such as cancer tissues, where rare mutations can drive metastasis and treatment response outcome. A major limitation of the clinical translation of single-cell analysis is the difficulty of isolating single cells from complex tissues. Our...

Published: 10/17/2022 | Inventor(s): Anubhav Tripathi, E. Celeste (Cel) Welch

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Category(s): Instruments, Research Tools

Placental lipid bilayer for cell-free molecular interaction studies

Overview Researchers and clinicians have a need for in vitro or in vivo tools to quantify placental interactions at the molecular scale. Lipid bilayers have been used to model biological interfaces, including those in the liver, red blood cells or myelin. We have developed a lipid bilayer that mimics the lipid composition of the placenta. Market...

Published: 10/17/2022 | Inventor(s): Anita Shukla, Christina Bailey-Hytholt, Anubhav Tripathi

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Category(s): Drug Delivery, Research Tools

Automated Microfluidic Cryo-TEM Sample Prep for Optimal Visualization (Case 1966)

Automated Microfluidic Blotless Specimen Preparation for Cryo-TEM Overview Transmission electron microscopy (TEM) is an important imaging tool in many physical and biological scientific fields. Because current methods for preparing the thin TEM specimens are specific to the material being analyzed and the information being sought, many different...

Published: 4/28/2020 | Inventor(s): Anubhav Tripathi, Jinkee Lee, Arijit Bose

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Category(s): Devices, Engineering and Sensors, Instruments, Nanotechnology, Research Tools

Biological Pick, Place, and Perfuse "BioP3" - Device to Engineer Thick Living Tissues with High Cell Density (Case 2220) (EA)

Engineering Thick Living Tissues with High Cell Density Overview The ability to build organs in vitro will have a far-reaching impact on the field of tissue engineering, as well as other areas of research that use animals. Cells cultured in 3D mimic native tissues and organs much more effectively than do those cultured in 2D. While significant advances...

Published: 4/7/2020 | Inventor(s): Jeffrey Morgan, Anubhav Tripathi, William Patterson Iii, John Murphy, Andrew Blakely

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Category(s): Devices, Nanotechnology, Research Tools, Stem Cells and Regenerative Medicine

Fast Detection of Hypervirulent Clostridium Difficile (Case 1952)

Fast Detection of Hypervirulent Clostridium Difficile Overview When a patient presents with symptoms of Clostridium difficile (C. difficile), rapid determination of the toxicity of the strain is of paramount importance; if a hypervirulent strain is identified, it is important to begin appropriate antimicrobial therapy as quickly as possible. Our...

Published: 4/7/2020 | Inventor(s): Anubhav Tripathi, Leonard Mermel, Aleksey Novikov, Jennifer Fieber, Leah Seward, Aartik Sarma

Keywords(s): Hospital Acquired Diseases, Nosocomial

Category(s): Diagnostics

Screening Method for Inhibitors of Multidrug-Resistance Transporters (Case 2079)

Novel Screening Method for Inhibitors of Multidrug-Resistant Transporters Overview Drug transport is of fundamental importance to the efficacy and toxicity of all drugs. From the route of administration to the site of action, a drug encounters numerous biological barriers, including efflux pumps that pump drugs out of cells. Our novel method uses...

Published: 8/16/2012 | Inventor(s): Jeffrey Morgan, Anubhav Tripathi, Toni-Marie Achilli (formerly Ferrucc, Stephanie Mccalla

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Category(s): Drug Delivery, Oncology, Research Tools, Diagnostics, Metabolic diseases