Search Results - Research Tools

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Intra Cellular Delivery of Small Molecules Using Novel Nanotechnology (Case 2060)
Affiliation: Brown UniversityProvidence, RIBrief Description: Pursuit of improved drug delivery vehicles continues to expand and grow with research focusing on a wide variety of approaches and necessary parameters, e.g., injectables, biocompatibility/degradability/availability, materials - polymers and nanoparticles...
Published: 2/2/2017   |   Inventor(s): Thomas Webster
Category(s): Diagnostics, Drug Delivery, Metabolic diseases, Nanotechnology, Neuroscience, Oncology, Research Tools, Stem Cells and Regenerative Medicine
Automated Microfluidic Cryo-TEM Sample Prep for Optimal Visualization (Case 1966)
Principal Investigators:Anubhav Tripathi, PhD, ProfessorJinkee Lee, PhD, Assistant ProfessorSchool of EngineeringBrown UniversityProvidence, RIArijit Bose, PhD, ProfessorDepartment of Chemical EngineeringUniversity of Rhode IslandKingston, RIBrief Description:Transmission electron microscopy (TEM) is a high resolution imaging technique whereby a small...
Published: 9/29/2016   |   Inventor(s): Anubhav Tripathi, Jinkee Lee, Arijit Bose
Category(s): Devices, Engineering and Sensors, Instruments, Nanotechnology, Research Tools
3D Cell Culture System to Uncover a Novel Target - In Fibrosis and Other Diseases (Case 2095)
Principal Investigators:Jeffrey Morgan, PhD, ProfessorDepartment of Molecular Pharmacology, Physiology and BiotechnologyAnubhav TripathiProfessor, School of EngineeringDepartment of Molecular Pharmacology, Physiology and BiotechnologyBrown UniversityProvidence, RIBrief Description:Fibrosis, a prevalent condition where excess connective tissue is accumulated...
Published: 12/17/2015   |   Inventor(s): Jeffrey Morgan, Anubhav Tripathi, Toni-Marie Achilli (formerly Ferrucc, Stephanie Mccalla, Jacquelyn Youssef Schell
Category(s): Devices, Nanotechnology, Research Tools, Stem Cells and Regenerative Medicine
Biological Pick, Place, and Perfuse "BioP3" - Device to Engineer Thick Living Tissues with High Cell Density (Case 2220) (EA)
Principal Investigator:Jeffrey Morgan, Ph. DProfessor – Molecular Pharmacology, Physiology and Biotechnology (MPPB) Brown UniversityProvidence, RIBrief Description:Approximately twenty-two people die in the United States everyday waiting for a life saving organ transplantation. The development of tissue-engineered organs to supplement our organ...
Published: 12/14/2015   |   Inventor(s): Jeffrey Morgan, Anubhav Tripathi, William Patterson Iii, John Murphy, Andrew Blakely
Category(s): Devices, Nanotechnology, Research Tools, Stem Cells and Regenerative Medicine
Novel Antibiotic Targets – Conserved Nucleotide Elements in Ribosomal RNA (Case 2211) (EA)
Principal Investigator:Susan A. Gerbi, Ph.D, Professor of BiochemistryDepartment of Bio Med Molecular, Cellular Biology BiochemistryBrown University Providence, RI Brief Description:Antibiotic resistance is a current and increasing threat to public health. Antibiotic resistant bacterial infections are difficult or even impossible to treat with our current...
Published: 12/4/2015   |   Inventor(s): Susan Gerbi, Benjamin Raphael, Julia Beamesderfer, Stephen Doris, Deborah Smith
Category(s): Research Tools, Therapeutics
High Throughput, High Spatial Resolution Whole Tissue Gene Expression Camera(EA) (Case 2157)
Principal Investigator:Casey Dunn, PhD, ProfessorDepartment of Ecology and Evolutionary BiologyBrown UniversityProvidence, RIBrief Description:At present, most gene expression studies can investigate only a small number of genes at high spatial resolution, or investigate a large number of genes at very poor spatial resolution. For many diagnostic and...
Published: 8/13/2015   |   Inventor(s): Casey Dunn
Category(s): Devices, Diagnostics, Engineering and Sensors, Instruments, Research Tools
Optimized, Cost Effective X-Ray Imaging that Rivals MRI: X-Ray Spatial Frequency Heterodyne Imaging with Protein-Based “Nanobubble” Contrast Agents (Case 2292)
Principal Investigator: Christoph Rose-Petruck, PhD, ProfessorDepartment of ChemistryBrown UniversityProvidence, RIBrief Description:Spatial Frequency Heterodyne Imaging (SFHI) is a novel x-ray scatter imaging technique that utilizes nanoparticle contrast agents. Previous studies on SFHI have utilized only metal nanoparticle contrast agents such as...
Published: 2/23/2015   |   Inventor(s): Christoph Rose-Petruck, Trevor Douglas, Danielle Rand, Masaki Uchida
Category(s): Diagnostics, Drug Delivery, Instruments, Nanotechnology, Oncology, Research Tools
Unique 3D Biomimetic Nanosurfaces for Growing Cells and Producing Cellular Implants (Case 1696)
Principal Investigator:Diane Hoffman-Kim, PhD, Associate Professor Department of Bio Med Molecular Pharmacology, Physiology and BiotechnologyBrown UniversityProvidence, RIBrief Description:An extensive list of polymers – natural and synthetic – has been utilized in drug delivery and in biomedical engineering for many years, especially...
Published: 2/6/2015   |   Inventor(s): Diane Hoffman-Kim
Category(s): Stem Cells and Regenerative Medicine, Devices, Drug Delivery, Nanotechnology, Research Tools, Therapeutics
Supergratings - Improved Detection and Processing of Optical Signals (Case 1466)
Principal Investigator:Jingming Xu, PhD, ProfessorSchool of EngineeringBrown UniversityProvidence, RIBrief Description:Gratings are optical devices used to achieve wavelength-dependent characteristics by means of optical interference effects. These wavelength-dependent optical characteristics can serve to reflect light of a specific wavelength while...
Published: 2/6/2015   |   Inventor(s): Daniel Levner, Martin Fay, Jingming Xu
Category(s): Devices, Engineering and Sensors, Instruments, Research Tools
Innovative Sublithographic Nanoscale Interfaces and Memory Architecture (Case 1545)
Principal Investigators: John Savage, PhD, ProfessorDepartment of Computer ScienceBrown UniversityProvidence, RIBrief Description:As computing devices become ever smaller, so do the accompanying microelectronic circuit boards and components. New advanced techniques beyond the conventional lithography of silicon for etching patterns and circuits in...
Published: 1/9/2015   |   Inventor(s): John Savage
Category(s): Devices, Drug Delivery, Engineering and Sensors, Nanotechnology, Research Tools
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