Search Results - Metabolic diseases

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Intra Cellular Delivery of Small Molecules Using Novel Nanotechnology (Case 2060)
Affiliation: Brown UniversityProvidence, RIBrief Description: Pursuit of improved drug delivery vehicles continues to expand and grow with research focusing on a wide variety of approaches and necessary parameters, e.g., injectables, biocompatibility/degradability/availability, materials - polymers and n...
Published: 2/2/2017   |   Inventor(s): Thomas Webster
Keywords(s):  
Category(s): Diagnostics, Drug Delivery, Metabolic diseases, Nanotechnology, Neuroscience, Oncology, Research Tools, Stem Cells and Regenerative Medicine
New and Improved Antibacterial Compounds (Case 2062)
Principal Investigator:Jason Sello, PhD, Assistant ProfessorDepartment of Chemistry Brown UniversityProvidence, RIBrief Description: Infectious diseases are the second leading cause of death – globally. Antibiotic drug resistance is a major clinical and societal problem, with m...
Published: 8/19/2015   |   Inventor(s): Jason Sello
Keywords(s):  
Category(s): Drug Delivery, Metabolic diseases, Oncology
Diagnosis and Treatment of Alzheimers' Disease (Case RIH-102)
Principal Investigators: Suzanne De La Monte, MD, MPH, ProfessorBio Med Pathology & Laboratory MedicineBrown UniversityProvidence, RIJack R. Wands, MD, ProfessorBio Med Molecular, Microbiology & ImmunologyBrown UniversityRhode Island HospitalProvidence, RIBrief Description:Alzheimer’s Disease (AD) is a debilitating disease primarily a...
Published: 5/23/2014   |   Inventor(s): S De La Monte, Jack Wands
Keywords(s):  
Category(s): Diagnostics, Metabolic diseases, Neuroscience, Therapeutics
Screening Method for Inhibitors of Multidrug-Resistance Transporters (Case 2079)
Principal Investigator: Jeffrey Morgan, PhD, ProfessorDepartment of Bio Med Molecular Pharmacology, Physiology and BiotechnologyBrown UniversityProvidence, RIBrief Description:Multidrug-resistance transporters (MDR) are protein pumps that are up regulated in diseased cells such as those in cancer patients. These proteins actively pump out benefic...
Published: 8/16/2012   |   Inventor(s): Jeffrey Morgan, Anubhav Tripathi, Toni-Marie Achilli (formerly Ferrucc, Stephanie Mccalla
Keywords(s):  
Category(s): Drug Delivery, Oncology, Research Tools, Diagnostics, Metabolic diseases
Advanced, Wireless, Implantable Neural Recording and Stimulation Microsystem (Case 2032)
Principal Investigator:Arto Nurmikko, PhD, ProfessorSchool of EngineeringBrown UniversityProvidence, RIBrief Description:With the advent of advanced materials, MEMs, microfluidics, nanotechnology and interdisciplinary research programs between engineering fields and the biomedical sciences, miniaturized, next generation devices are now being develo...
Published: 6/20/2012   |   Inventor(s): Arto Nurmikko
Keywords(s):  
Category(s): Devices, Diagnostics, Drug Delivery, Engineering and Sensors, Metabolic diseases, Nanotechnology, Neuroscience, Oncology, Research Tools, Stem Cells and Regenerative Medicine
Improved Method of Manufacturing Nanowire Nanoarray Memories (Case 1709)
Principal Investigator: John Savage, PhD, Professor Department of Computer ScienceBrown UniversityProvidence, RIBrief Description:Methods have been developed for growing nanowires (NWs) and carbon nanotubes (NTs) with diameters of a few nanometers and for assembling NWs into nanoarrays, crossbars containing two orthogonal sets of parallel wires on...
Published: 6/20/2012   |   Inventor(s): John Savage, Eric Rachlin, Andre Dehon, Charles Lieber
Keywords(s):  
Category(s): Devices, Diagnostics, Engineering and Sensors, Environmental, Metabolic diseases, Nanotechnology, Neuroscience, Oncology, Research Tools, Software, Stem Cells and Regenerative Medicine
Interactive, Multilayer, Multivalued Volume-Rendering for Superior 3D Images from MRI or Other Data (Case 1492)
Principal Investigator:David Laidlaw, PhD, ProfessorDepartment of Computer ScienceBrown UniversityProvidence, RIBrief Description:Magnetic resonance imaging (MRI) is a well-established and powerful technique for elucidating structure and is used, for example, in medical applications to discriminate between normal and pathological tissue. The MRI i...
Published: 6/11/2012   |   Inventor(s): David Laidlaw, Andreas Wenger
Keywords(s):  
Category(s): Devices, Diagnostics, Engineering and Sensors, Instruments, Metabolic diseases, Neuroscience, Oncology, Research Tools, Software, Stem Cells and Regenerative Medicine
Improved, Scalable, Optical Particle/Molecule Detector System by Solid State Energy Sources (Case 1494)
Principal Investigator:Arto Nurmikko, PhD, ProfessorSchool of EngineeringBrown UniversityProvidence, RIBrief Description:With environmental safety and defense/bioterrorism concerns, and the continuing drive for important medical breakthroughs, quick and accurate particle diagnostic capabilities have become increasingly important to identify and qua...
Published: 6/11/2012   |   Inventor(s): Arto Nurmikko, Richard Chang
Keywords(s):  
Category(s): Devices, Diagnostics, Energy, Engineering and Sensors, Environmental, Instruments, Metabolic diseases, Nanotechnology, Neuroscience, Oncology, Research Tools, Stem Cells and Regenerative Medicine
Innovative, Fully Redox-Active Monomers and Polymers with Broad Applications (Case 1702)
Principal Investigator:Tayhas Palmore, PhD, ProfessorSchool of EngineeringBrown UniversityProvidence, RIBrief Description:Interest in redox-active polymers stems from their application in electrochromic devices, biofuel cells, and biosensors all of which require a high concentration of electron mediators that are non-leachable. The molecule 2,2&rs...
Published: 12/6/2011   |   Inventor(s): Tayhas Palmore, Hyun-Kon Song
Keywords(s):  
Category(s): Devices, Diagnostics, Energy, Engineering and Sensors, Environmental, Metabolic diseases, Research Tools
Advanced, Sensitive, Broad Tractography Metrics to Characterize Cerebral White Matter (Case 1732)
Principal Investigator: David Laidlaw, PhD, Professor Department of Computer ScienceBrown UniversityProvidence, RIBrief Description:Diffusion tensor imaging (DTI) is a magnetic resonance imaging (MRI) technique that measures the directionally dependent rate of water self-diffusion in each image voxel or volumetric picture element - a 3-dimensional...
Published: 12/6/2011   |   Inventor(s): David Laidlaw, Song Zhang, Stephanie Lee
Keywords(s):  
Category(s): Devices, Diagnostics, Environmental, Instruments, Metabolic diseases, Neuroscience, Oncology, Research Tools, Software, Stem Cells and Regenerative Medicine
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