Search Results - Neuroscience

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Implantable Wireless Network of Distributed Microscale Sensors for Neural Applications
­Wireless Network of Neural Implants for Brain-Machine Interfaces Overview The field of brain-machine interfaces has advanced significantly over the past two decades, especially in its successful transition into human clinical trials. This progress has relied largely on wired, invasive sensors for the acquisition of neural data with high spatial...
Published: 11/29/2021   |   Inventor(s): Arto Nurmikko, Farah Laiwalla, Lawrence Larson, Jihun Lee, Patrick Mercier, Peter Asbeck, Vincent Leung
Keywords(s):  
Category(s): Neuroscience
Adaptive, Wireless Microchiplet Network for Large Scale Cortical Sensing and Stimulation
Wireless Network of Neural Implants for Brain-Machine Interfaces Overview The field of brain-machine interfaces has advanced significantly over the past two decades, especially in its successful transition into human clinical trials. This progress has relied largely on wired, invasive sensors for the acquisition of neural data with high spatial and...
Published: 11/29/2021   |   Inventor(s): Arto Nurmikko, Lawrence Larson, Farah Laiwalla, Peter Asbeck, Ramesh Rao, Vincent Leung, Patrick Mercier, Jihun Lee
Keywords(s):  
Category(s): Neuroscience
Peel-Away Electrode Placement Catheter for Deep Brain Stimulation (DBS)
­Brown’s Laboratory for Neurophysiology and Neuromodulation The Laboratory for Neurophysiology and Neuromodulation studies neural circuits in humans and nonhuman animal models to understand action planning, learning, and high-level cognition, to place neurological and psychiatric dysfunction into these mechanistic contexts, and to design...
Published: 11/1/2021   |   Inventor(s): Wael Asaad, Shane Lee, Owen Leary, Noah Trac, Zakir Tahiry, Rohan Rastogi
Keywords(s):  
Category(s): Central Nervous System(CNS), Devices, Neuroscience
Continuous motor task for objectively quantifying motor symptoms in movement disorders
­Brown’s Laboratory for Neurophysiology and Neuromodulation The Laboratory for Neurophysiology and Neuromodulation studies neural circuits in humans and nonhuman animal models to understand action planning, learning, and high-level cognition, to place neurological and psychiatric dysfunction into these mechanistic contexts, and to design...
Published: 11/1/2021   |   Inventor(s): Wael Asaad, Shane Lee, Minkyu Ahn, James Yu, Daniel Amaya, David Liu, Peter Lauro
Keywords(s):  
Category(s): Central Nervous System(CNS), Neuroscience, Devices
Novel Compounds for Treatment of Neurodegenerative Conditions and Diseases (Case 1939)
Novel Compounds for Treatment of Neurodegenerative Conditions and Diseases Overview Stroke and other neurological insults entail a build-up of waste materials in brain cells. One of the most common waste materials is glutamate, which is present in more than 50 percent of nervous tissue. Glutamate receptors are critical to neuronal functioning. Failure...
Published: 8/11/2021   |   Inventor(s): John Marshall, Mark Spaller, Dennis Goebel
Keywords(s):  
Category(s): Neuroscience, Research Tools, Therapeutics
Method to Predict and Diagnose Seizures and Other Neurological Events (Case 2045)
Method to Predict and Diagnose Seizures and Other Neurological Events Overview Though epilepsy is a common neurological disorder, the medical community still struggles to define and understand seizures and related neurological events. Our method uses implanted microelectrode arrays to predict and detect neurological events—a crucial first step...
Published: 2/3/2021   |   Inventor(s): John Donoghue, Leigh Hochberg, Wilson Truccolo
Keywords(s):  
Category(s): Diagnostics, Instruments, Neuroscience, Software
Optogenetic Control of the Blood Brain Barrier for Drug Delivery (Case 2135)
Optogenetic Control of the Blood Brain Barrier for Drug Delivery Overview The blood–brain barrier (BBB) remains a significant impediment to drug development for central nervous system (CNS) disorders. Our novel method provides a way to regulate the permeability of the BBB, enabling delivery of therapeutics to the brain with high spatial and temporal...
Published: 4/28/2020   |   Inventor(s): Christopher Moore, Tyler Brown
Keywords(s):  
Category(s): Engineering and Sensors, Drug Delivery, Neuroscience, Oncology, Therapeutics
Intracranial Fixation Device for Probes and Catheters (Case 2253)
Brown’s Laboratory for Neurophysiology and Neuromodulation The Laboratory for Neurophysiology and Neuromodulation studies neural circuits in humans and nonhuman animal models to understand action planning, learning, and high-level cognition, to place neurological and psychiatric dysfunction into these mechanistic contexts, and to design improved...
Published: 4/28/2020   |   Inventor(s): Wael Asaad, David Segar
Keywords(s):  
Category(s): Central Nervous System(CNS), Devices, Neuroscience
Improved Method of Manufacturing Nanowire Nanoarray Memories (Case 1709)
Principal Investigator: John Savage, PhD, Professor Department of Computer ScienceBrown UniversityProvidence, RIBrief Description:Methods have been developed for growing nanowires (NWs) and carbon nanotubes (NTs) with diameters of a few nanometers and for assembling NWs into nanoarrays, crossbars containing two orthogonal sets of parallel wires on...
Published: 4/28/2020   |   Inventor(s): John Savage, Eric Rachlin, Andre Dehon, Charles Lieber
Keywords(s):  
Category(s): Devices, Diagnostics, Engineering and Sensors, Environmental, Metabolic diseases, Nanotechnology, Neuroscience, Oncology, Research Tools, Software, Stem Cells and Regenerative Medicine
Minimally-Invasive and Activity Dependent Control of Excitable Neurons (Case 2333)
Minimally Invasive Optogenetic Control of Excitable Neurons Overview Optogenetics uses light to modulate excitable cells containing light-sensitive ion channels, known as opsins When activated by light, opsins cause depolarization or hyperpolarization of cell membranes, resulting in cellular excitation or silencing on a short time scale. Our minimally...
Published: 3/30/2020   |   Inventor(s): Christopher Moore, Ute Hochgeschwender
Keywords(s):  
Category(s): Neuroscience, Therapeutics
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