Search Results - Neuroscience

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Minimally-Invasive and Activity Dependent Control of Excitable Neurons (Case 2333)
Principal Investigator:Christopher Moore, PhD, Associate ProfessorDepartment of NeuroscienceBrown UniversityProvidence, RIBrief Description:Abnormal cellular bursting is involved in a number of disease states. These include Parkinson’s Disease, affecting 1 million Americans and incurring an annual cost of $25 billion, and epilepsy, affecting 2 million...
Published: 3/30/2020   |   Inventor(s): Christopher Moore, Ute Hochgeschwender
Category(s): Neuroscience, Therapeutics
Intra Cellular Delivery of Small Molecules Using Novel Nanotechnology (Case 2060)
Affiliation:                     Brown UniversityProvidence, RIBrief Description:                          Pursuit of improved drug delivery vehicles continues to expand and grow with research focusing on a wide variety of approaches and necessary parameters, e.g., injectables, biocompatibility/degradability/availability, materials - polymers and nanoparticles...
Published: 2/2/2017   |   Inventor(s): Thomas Webster
Category(s): Diagnostics, Drug Delivery, Metabolic diseases, Nanotechnology, Neuroscience, Oncology, Research Tools, Stem Cells and Regenerative Medicine
Fully Mobile Virtual Reality System (Case 2242)
Principal Investigators:William Warren, PhD, ProfessorDepartment of Cognitive, Linguistic, and Psychological SciencesGabriel Taubin, PhD, Associate Professor School of of EngineeringBrown UniversityProvidence, RIBrief Description:Virtual Reality is here. High-speed, high-definition, low-cost, thrilling VR has arrived.  With Facebook’s purchase of the...
Published: 11/24/2015   |   Inventor(s): William Warren, Michael William Fitzgerald
Category(s): Devices, Software, Neuroscience
Treatment for Microcephaly-Associated Neurodevelopmental Disorders, Including Rare X-Linked Christianson’s Syndrome (Case 2192)
Principal Investigator:Eric Morrow, PhD, Associate ProfessorDepartment of Bio Med Molecular, Cellular Biology BiochemistryBrown UniversityProvidence, RIBrief Description:Intellectual and developmental disabilities (IDD) affect an estimated 4.6 million people in the US with annual costs in the range of $386BB. There are few bio-therapeutic options to...
Published: 11/24/2015   |   Inventor(s): Eric Morrow
Category(s): Neuroscience, Therapeutics
Optogenetic Control of the Blood Brain Barrier for Drug Delivery (Case 2135)
Principle Investigator:Christopher Moore, PhD, Associate Professor Department of NeuroscienceBrown UniversityBrief Description:The blood-brain-barrier (BBB) blocks approximately 98% of small molecule therapeutics and almost 100% of large molecular therapeutics from reaching the central nervous system, creating a challenge in drug delivery for treatment...
Published: 11/24/2015   |   Inventor(s): Christopher Moore, Tyler Brown
Category(s): Engineering and Sensors, Drug Delivery, Neuroscience, Oncology, Therapeutics
Pain Management – Medical Device (Case RIH-136)
Principal Investigator:Carl Saab, PhD, Assistant ProfessorDepartment of Bio Med NeurosurgeryBrown UniversityProvidence, RIBrief Description:Chronic pain remains a daunting medical condition for growing numbers of patients worldwide whether it is associated with other disease conditions as a symptom or as a stand-alone syndrome.  Often treatments are...
Published: 3/13/2015   |   Inventor(s): Carl Saab
Category(s): Devices, Central Nervous System(CNS), Neuroscience, Therapeutics, Diagnostics
Wearable Computer-Vision Rig for the Visually Impaired (Case 2241)
Principal Investigator:Benjamin Kimia, PhD, ProfessorSchool of EngineeringBrown UniversityProvidence, RIBrief Description:It is estimated that there are 285 million Visually Impaired (VI) people worldwide: 39 million are blind, 246 million have low vision. There are about 10 million VI people in the US whose disability affects them and their family...
Published: 3/13/2015   |   Inventor(s): Benjamin Kimia
Category(s): Devices, Engineering and Sensors, Neuroscience, Software
Intracranial Fixation Device for Probes and Catheters (Case 2253)
Principal Investigator:Wael Asaad, MD, PhD, Assistant ProfessorDepartment of NeurosurgeryRhode Island Hospital, Brown UniversityProvidence, RIBrief Description:                             Deep Brain Stimulation (DBS) and other intracranial procedures that involve probe insertion require accurate and solid fixation to the skull for optimal clinical...
Published: 8/8/2014   |   Inventor(s): Wael Asaad, David Segar
Category(s): Central Nervous System(CNS), Devices, Neuroscience
Diagnosis and Treatment of Alzheimers' Disease (Case RIH-102)
Principal Investigators: Suzanne De La Monte, MD, MPH, ProfessorBio Med Pathology & Laboratory MedicineBrown UniversityProvidence, RIJack R. Wands, MD, ProfessorBio Med Molecular, Microbiology & ImmunologyBrown UniversityRhode Island HospitalProvidence, RIBrief Description:Alzheimer’s Disease (AD) is a debilitating disease primarily affecting adults...
Published: 5/23/2014   |   Inventor(s): S De La Monte, Jack Wands
Category(s): Diagnostics, Metabolic diseases, Neuroscience, Therapeutics
Advanced, Wireless, Implantable Neural Recording and Stimulation Microsystem (Case 2032)
Principal Investigator:Arto Nurmikko, PhD, ProfessorSchool of EngineeringBrown UniversityProvidence, RIBrief Description:With the advent of advanced materials, MEMs, microfluidics, nanotechnology and interdisciplinary research programs between engineering fields and the biomedical sciences, miniaturized, next generation devices are now being developed...
Published: 6/20/2012   |   Inventor(s): Arto Nurmikko
Category(s): Devices, Diagnostics, Drug Delivery, Engineering and Sensors, Metabolic diseases, Nanotechnology, Neuroscience, Oncology, Research Tools, Stem Cells and Regenerative Medicine
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