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Two Compartment Model for Detecting the Toxicity of Liver Metabolites
Overview Liver toxicity is a significant reason many new drugs fail in clinical trials. Primary human hepatocytes (PHHs) are the current gold standard for in vitro liver models; however, they have a number of limitations. We have invented an easy-to-use two-compartment device that provides in vitro 3D high-throughput prediction for safety assessments...
Published: 5/20/2024
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Inventor(s):
Kim Boekelheide
,
Jeffrey Morgan
,
Blanche Ip
,
Susan Hall
,
Hui Li
Keywords(s):
Category(s):
Diagnostics
Method for Making Small Diameter Living Tubes
Overview We have developed a funnel-guide device for the noncontact manipulation and positioning of multicellular microtissues, to build macrotissues layer by layer. One specific application is the fabrication of biological tubes. Market Opportunity A long-standing problem in 3D tissue engineering is how to fabricate large tissue constructs with...
Published: 12/21/2022
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Inventor(s):
Jeffrey Morgan
,
Kali Manning
,
Blanche Ip
Keywords(s):
Category(s):
Stem Cells and Regenerative Medicine
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