Intracranial Fixation Device for Probes and Catheters (Case 2253)

Principal Investigator:


Wael Asaad, MD, PhD, Assistant Professor
Department of Neurosurgery

Rhode Island Hospital, Brown University

Providence, RI


Brief Description:


Deep Brain Stimulation (DBS) and other intracranial procedures that involve probe insertion require accurate and solid fixation to the skull for optimal clinical outcome. The high cost and surgical complexity of DBS and intracranial procedures using existing fixation devices remain as challenges in the market, creating opportunities for cost-effective, simple and reliable devices to support the optimal clinical outcomes.


The invention is an electrode stabilization device for incorporation into a skull plating system.  The device serves as a skull anchor and is an elegantly simple means to secure intracranial probes and catheters, including DBS electrodes and shunts.  The device is for use by neurosurgeons during the implantation of neural probes such as (but not limited to) deep brain stimulating electrodes, recording electrodes, optical probes, dialysis probes, injection cannulae and aspiration cannulae / fluid shunts.  A 3D printed prototype and data are available for this technology.  This innovative device has the advantages of no moving parts or interlocking pieces while providing a simple, secure and effective way to anchor the skull during procedures, thereby improving clinical outcomes, cosmetic results, and potentially reducing procedure (anesthetic) time by eliminating the need for and risk related to over complicated surgical manipulations associated with other devices.

Applications include for use in securing DBS electrodes in-place, as when placed to treat diseases such as Parkinson’s, essential tremor and dystonia, etc. Other examples of intended use: secure cerebrospinal fluid shunt catheters, as when placed to treat diseases such as hydrocephalus; secure infusion catheters, such as those used in the GAD-AAV study for Parkinson’s Disease; and secure light-delivery devices (e.g., fiber optic catheters), as for optogenetic approaches to neuromodulation.



US patent application 14/528,580 is pending.

Patent Information:
For Information, Contact:
Margaret Shabashevich,
Manager of Operations
Office of Industry Engagement & Commercial Venturing
Brown University
Wael Asaad
David Segar
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