Search Results - Neurodegenerative+Disease

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New use of CsA-type drugs for the prevention and treatment of neurodegenerative disorders, including Alzheimer’s disease
­Novel Method Repurposes CsA-Type Compounds to Treat Neurodegenerative Disease Overview Alzheimer’s disease remains a challenging disorder for drug development, with many candidate drugs failing clinical trials. Our novel method repurposes camphorsulfonic acid (CsA)-type compounds to treat early-stage Alzheimer’s disease, as well as...
Published: 4/29/2022   |   Inventor(s): Robbert Creton
Keywords(s):  
Category(s): Therapeutics, Neurodegenerative Disease
A novel nucleocytoplasmic regulator of autophagy-associated transcription factors stimulates autophagy and prevents the proteostatic decline associated with neurodegeneration
­Activating Autophagy to Prevent Neurodegeneration and Extend Lifespan Overview Decline in proteostasis is a hallmark of age-related neurodegerative disease such as Alzheimer’s Disease. Autophagy is the process by which cells rid themselves of damaged or otherwise unnecessary material, which then moves to the lysosome and degrades. Pharmacologic...
Published: 2/22/2022   |   Inventor(s): Louis Lapierre
Keywords(s):  
Category(s): Therapy Targets, Neurodegenerative Disease
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