Search Results - yu-wen+huang

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First in class use of the estrogen receptor-b agonist in treating Angelman syndrome and relevant autism spectrum disorders

Overview Angelman syndrome is a genetic disorder caused by UBE3A gene dysfunction, leading to cognitive impairment, motor coordination issues, and developmental delays. Research suggests that oligodendroglial dysfunction, which affects myelination in the brain, contributes to these conditions. Based on the research, this invention discloses a novel...

Published: 3/6/2025 | Inventor(s): Yu-Wen Huang, Xin Yang

Keywords(s):

Category(s): Genetic Diseases, Therapeutics, Therapy Targets

Use of CRTH2 Antagonist to Treat Neuromyelitis Optica and Other Autoimmune Disorders of the Central Nervous System

Overview The detrimental effects of neuroinflammation, especially neuromyelitis optica spectrum disorder (NMOSD), on cognitive performance can include severe vision loss, motor deficits, and cognitive decline. We have invented a method that targets the detrimental effects of neuroinflammation on cognitive performance by using a CRTH2 (chemoattractant...

Published: 6/7/2023 | Inventor(s): Yu-Wen Huang, Changyong Tang, Wei Qiu, Yaxiong Cui

Keywords(s):

Category(s): Central Nervous System(CNS), Therapeutics