New Composition for Biologics (Case 2289)

Principal Investigator(s):

 

Edith Mathiowitz, Ph.D.

Professor of Medical Science and Engineering

Director of the Graduate Program in Biotechnology

 

Brown University

Providence, RI

 

Brief Description:

 

The market for protein/peptide-based therapeutics has become decidedly established in the past decade, although the gastrointestinal tract causes a significant drug-delivery challenge. As a consequence, most protein-based drugs must be delivered intravenously or subcutaneously.

 

Brown University researchers have established a nanoparticle delivery system contained in a PEG/pluronic F127 matrix. This composition stabilizes these proteins for any route of administration – oral, vaginal, injectable and rectal, as well as inhalation providing numerous new drug delivery solutions for drug makers.

 

Information:

 

PCT application PCT/2015/045402 is pending.

 

Patent Information:
Category(s):
Drug Delivery
For Information, Contact:
Margaret Shabashevich,
Manager of Operations
Technology Ventures Office
Brown University
401-863-7499 TVO_Patents@brown.edu
Inventors:
Edith Mathiowitz
Nejat Egilmez
Stacia Furtado
Thomas Conway
Keywords:
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